Lipoprotein(a) as well as two oxidized phospholipids (OxPLs) are all associated with multivessel coronary artery disease detected on angiography and also linked to a higher risk of major adverse ...

Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...

Lipids are fatty compounds that perform a range of essential functions in the body. Phospholipids, steroids, and triglycerides are examples of lipids. Although lipids play an essential role in the ...

The TMEM16 family of membrane proteins was hailed as representing the elusive calcium-activated chloride channels. However, the majority of the family members turned out to be scramblases, proteins ...

New progress in a long-standing debate about the nature of biological cell membranes could be made by considering which aspects of the membrane can be captured in simplified simulations. ABC ...

In biological systems, phospholipids are made by enzymes embedded in preexisting phospholipid membranes. Such circular dependence has hindered the development of methods for making membranes for ...

An ribonucleic acid (RNA) inhibitor, olpasiran (Amgen), which has shown it can lower lipoprotein(a) [Lp(a)] levels in patients with cardiovascular disease (CVD), has demonstrated in a phase 2 trial ...

Lipids are a diverse group of organic compounds that are essential for several biological functions, ranging from energy storage to cell signaling. They are loosely described as organic, ...