Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...
Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation.
The viral transposable element, MERVL, acts as a central switch during early embryonic development, driving totipotent gene ...
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