Blue Eyes Genetics: OCA2 Gene | Genes in Action
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The appearance of blue eyes traces back to a single, spontaneous mutation in the OCA2 gene that occurred in an individual near the Black Sea between 6,000 and 10,000 years ago. Before this, brown was the predominant eye color. The mutation doesn't create blue pigment; rather, it acts as a 'switch' that reduces melanin production in the iris. This causes light to scatter in a way that makes the eyes appear blue, a phenomenon known as the Tyndall effect. This genetic trait emerged during the Neoli
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